“Actin Cytoskeleton”

Devices such as hard drives, CDs, and DVDs provide storage for nearly all of the world’s information, but less is known about the storage potential of biological materials.

Seed like nucleators play a role in controlling the assembly of cell scaffolding.
Image courtesy: Yale University

Researchers at the Yale Systems Biology Institute have found that it is possible to store information in the protein polymer network – or “actin cytoskeleton” – that forms the mechanical scaffolding within our cells, and which is responsible for maintaining and changing cell shape.

Published in the journal Advanced Functional Materials, the scholars describe the organizational role of a seed-like nucleator called ‘formin’ in controlling the rate of assembly of the polymer network.

By tuning the density of the seeds and their rate of network assembly, the scientists were able to control the architecture and shape of the actin polymer network, effectively like encoding new biological memory. Advancing our understanding of polymer mechanics opens the way for biological principles to be used in future memory storage devises.

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